UPSC Prelims 2021 · GS Paper 1 · Q36

Science & Technology

Medium · Mitochondrial Inheritance and Replacement Therapy

Consider the following statements regarding the inheritance and prevention of mitochondrial hereditary diseases:

1. Techniques such as maternal spindle transfer before fertilisation, or pronuclear transfer after in vitro fertilisation, can prevent transmission of mitochondrial disease from mother to child.

2. A child inherits mitochondrial DNA, and any associated mitochondrial disease, only from the mother, since mitochondria are passed on almost entirely through the egg cytoplasm.

Which of the statements given above is/are correct?